Ya, the LS1's are more prone to detonation due to the lack of reverse cooling, but a little birdie told me that a new water pump is being developed to reverse cool the LS1s for FI applications.
Rob & Jack are both dead on the additional implications of FI...pistons, clutches, rearends and stock fuel systems are the major weak links.
LoL Jack...wouldn't that Stage 3 Incon set-up be nice?
Rob, Turbo Tech in Tacoma, Wa is the main shop doing the LT1 turbo setup. They have had one on a test car for the past 3 months, but are having problems with the intercooler keeping the charge cool and some minor PCM tuning problems.